Authors: Farnaz Sedighin, Maryam Monemian, Zahra Zojaji, Ahmadreza Montazerolghaem, Mohammad Amin Asadinia, Seyed Mojtaba Mirghaderi, Seyed Amin Naji Esfahani, Mohammad Kazemi, Reza Mokhtari, Maryam Mohammadi, Mohadese Ramezani, Mahnoosh Tajmirriahi, Hossein Rabbani
Date published: 2025/1/1
Publisher: Medknow
Vol. 15, page.10.4103, Issue.1
Abstract
Background: Computer-aided diagnosis (CAD) methods have become of great interest for diagnosing
macular diseases over the past few decades. Artificial intelligence (AI)-based CADs offer several
benefits, including speed, objectivity, and thoroughness. They are utilized as an assistance system
in various ways, such as highlighting relevant disease indicators to doctors, providing diagnosis
suggestions, and presenting similar past cases for comparison. Methods: Much specifically, retinal
AI-CADs have been developed to assist ophthalmologists in analyzing optical coherence tomography
(OCT) images and making retinal diagnostics simpler and more accurate than before. Retinal AI-
CAD technology could provide a new insight for the health care of humans who do not have access
to a specialist doctor. AI-based classification methods are critical tools in developing improved retinal
AI-CAD technology. The Isfahan AI-2023 challenge has organized a competition to provide objective
formal evaluations of alternative tools in this area. In this study, we describe the challenge and those
methods that had the most successful algorithms. Results: A dataset of OCT images, acquired from
normal subjects, patients with diabetic macular edema, and patients with other macular disorders,
was provided in a documented format. The dataset, including the labeled training set and unlabeled
test set, was made accessible to the participants. The aim of this challenge was to maximize the
performance measures for the test labels. Researchers tested their algorithms and competed for the
best classification results. Conclusions: The competition is organized to evaluate the current AI-
based classification methods in macular pathology detection. We received several submissions to our
posted datasets that indicate the growing interest in AI-CAD technology. The results demonstrated
that deep learning-based methods can learn essential features of pathologic images, but much care
has to be taken in choosing and adapting appropriate models for imbalanced small datasets.